What is misoprostol?
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Misoprostol reduces stomach acid and helps protect the stomach lining from damage that can be caused by taking aspirin or a nonsteroidal anti-inflammatory drug (NSAID).
Misoprostol is a synthetic prostaglandin that works by “replacing” prostaglandins whose production is blocked by aspirin or NSAIDs. It is used to prevent stomach ulcers from developing during treatment with aspirin or an NSAID. Examples of NSAIDs include ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, and meloxicam.
Misoprostol is used in a hospital setting to induce cervical ripening, labor induction in women with premature rupture of membranes, and treatment of serious post-partum hemorrhage, These uses are outside of the approved indications.
Misoprostol is also in combination with mifepristone or methotrexate to end an early pregnancy (medical abortion) or alone for early pregnancy loss (miscarriage).
- Although FDA regulations allow certified healthcare professionals and pharmacies to dispense mifepristone and misoprostol for medical abortion both in healthcare facilities and by telehealth and mail, certain state laws may not allow this. For example, Louisiana has passed a bill that classifies mifepristone and misoprostol as dangerous controlled substances which, once signed, would mean anyone possessing these abortion pills without a prescription could face jail time and fines. Most abortions are already illegal in Louisiana.
When used for non-pregnancy-related conditions, misoprostol should not be used during pregnancy, and if you can become pregnant, you will need to have a negative pregnancy test before starting this treatment.
Before Using|buy misoprostol online
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric|buy misoprostol online
Appropriate studies have not been performed on the relationship of age to the effects of misoprostol in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of misoprostol in the elderly.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Misoprostol may cause serious side effects. Call your doctor at once if you have:
- severe ongoing stomach discomfort or diarrhea; or
- dehydration–dizziness, confusion, feeling very thirsty, less urination.
Dosing
The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For oral dosage form (tablets):
- To prevent stomach ulcers in patients taking NSAIDs:
- Adults—200 micrograms (mcg) 4 times a day. Other patients may need 100 mcg 4 times a day. Take the last dose of the day at bedtime.
- Children—Use and dose must be determined by your doctor.
- To prevent stomach ulcers in patients taking NSAIDs:
Missed Dose
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.buy misoprostol online
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